Antiparasitic effect of limonene, a monoterpene compound found in the essential oils against Giardia lamblia

نویسندگان

چکیده

Introduction: The present work aimed to assess the anti-parasitic effects of limonene (LMN) against Giardia lamblia trophozoites and cysts. Methods: Anti-Giardia activities LMN (25, 50, 100 μg/mL) were assessed G. cysts for 15-360 minutes. on apoptosis stimulation parasites determined by colorimetric protease assay. Results: more sensitive than best effect was seen at μg/mL. markedly triggered caspase-3 activity 10.2%, 25.3%, 36.1%, respectively (P < 0.001). Conclusion: We found potent in vitro anti-giardia with maximum 50 However, additional surveys are necessary reveal specific efficacy, mechanisms, safety LMN.

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ژورنال

عنوان ژورنال: Journal of HerbMed Pharmacology

سال: 2023

ISSN: ['2345-5004']

DOI: https://doi.org/10.34172/jhp.2023.34